Neutropenic fever: When to cover MRSA?

When to suspect high risk MRSA and S. viridans in neutropenic fever?

Do all neutropenic fever initial treatment shall be added up with IV Vancomycin?

Those are the risk factors:
1) Mucositis
2) Skin infection
3) History of colonization with MRSA
4) Recent prophylaxis using fluoroquinolones
5) Catheter-site infection

Reserve the vancomycin use for institutions with high rate of MRSA or S. viridans.

Source: BMJ (Oct 2018)

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