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Midazolam - Morphine Dilution

Mida-Morphine for sedation may vary from other healthcare institution.

Preparation available in KKM:
1) Midazolam injection: 5mg/ml, 15mg/3ml
2) Morphine Injection: 10mg/ml

Dilute:
||| Midazolam 30mg (6ml) ||| + ||| Morphine 30mg (3ml) |||
in
21ml Normal Saline (qs. 30ml)
in 50cc syringe
~ ~ ~
Midoazolam 1mg/ml and Morphine 1mg/ml
 
1. May give loading dose of 0.05 mg/kg midazolam
2. Start at 0.06 mcg/kg/hr of midazolam
3. Dose range: 0.06 - 2 mg/kg/hr
4. May increase by 1ml/hr every 20 minutes till target RASS -2 to +1 achieved

 
 
Source: Medication Reconstitution & Medication Dilution Reference 2013 HSAJB

Comments

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Midazolam - Fentanyl Sedation

DILUTION PROTOCOL for mida-fentanyl may vary from other health institution. Preparation for each dosage form: 1. Inj Midazolam : 5mg/1ml and 15mg/3ml 2. Inj Fentanyl : 100mcg/2ml Dilution: |||||||  30MG MIDAZOLAM |||||| + ||||||  300MCG FENTANYL |||||| dilute in  30ML NORMAL SALINE in 50ML syringe For every 1ml/hr,  1mg/hr midazolam + 10mcg/ml fentanyl  is administered. Infusion starting dose : 3 ml/hr Titrate to the desired effect Bolus dose may be required for faster effect ( 3 - 5 mls), followed by infusion dose. Source: ETD HSAJB